Description

3-Iodo-6-Methyl-5-Nitro-7-Azaindole is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters because it serves as a critical precursor in the development of novel pharmaceutical agents and agrochemicals, enabling the construction of complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating targeted bioactive molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of kinase inhibitors and other small-molecule drug candidates targeting various disease pathways.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its heterocyclic core for bioactivity.
• Chemical Biology Probe: Serves as a versatile scaffold for creating molecular probes to study enzyme function and cellular processes.
• Material Science Precursor: Employed in the synthesis of organic electronic materials and advanced polymers due to its electron-deficient aromatic system.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create diverse biaryl structures.
• Library Synthesis for HTS: A valuable building block for generating focused compound libraries used in high-throughput screening (HTS) campaigns.

Basic Information

Product Name	3-Iodo-6-Methyl-5-Nitro-7-Azaindole
CAS No.	1000340-21-5
Molecular Formula	C8H6IN3O2
Molecular Weight	303.06 g/mol
Synonyms	3-Iodo-6-methyl-5-nitro-1H-pyrrolo[2,3-b]pyridine; 5-Nitro-6-methyl-3-iodo-7-azaindole; 1H-Pyrrolo[2,3-b]pyridine, 3-iodo-6-methyl-5-nitro-; 3-Iodo-6-methyl-5-nitropyrazolopyridine; 7-Azaindole, 3-iodo-6-methyl-5-nitro-; 1000340-21-5; 3-Iodo-6-methyl-5-nitro-1H-7-azaindole
EINECS	Contact for details

Quality Control

Our 3-Iodo-6-Methyl-5-Nitro-7-Azaindole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.