Description

2-[4-(Trifluoromethyl)Piperidino]-1,3-Thiazole-5-Carbaldehyde is a high-value, multi-functional heterocyclic building block featuring a thiazole core substituted with a carbaldehyde group and a trifluoromethylated piperidine moiety. This compound matters for its unique structural profile, which combines the metabolic stability and lipophilicity imparted by the trifluoromethyl group with the versatile reactivity of the aldehyde functional group. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in areas like kinase inhibitors, antiviral agents, and central nervous system (CNS) therapeutics.
• Agrochemical Research: Serves as a precursor in the design and synthesis of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiazole ring.
• Material Science Chemistry: Used in the synthesis of specialty chemicals, ligands for catalysis, and advanced organic materials.
• Chemical Biology & Proteomics: The reactive aldehyde group makes it suitable for bioconjugation strategies and as a scaffold for probe or linker development.
• Custom Synthesis & Contract Manufacturing: An essential building block for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	2-[4-(Trifluoromethyl)Piperidino]-1,3-Thiazole-5-Carbaldehyde
CAS No.	1000339-88-7
Molecular Formula	C10H11F3N2OS
Molecular Weight	264.27 g/mol
Synonyms	2-[4-(Trifluoromethyl)-1-piperidinyl]-1,3-thiazole-5-carboxaldehyde; 5-Formyl-2-[4-(trifluoromethyl)piperidino]thiazole; 2-(4-Trifluoromethylpiperidin-1-yl)thiazole-5-carbaldehyde; 1,3-Thiazole-5-carboxaldehyde, 2-[4-(trifluoromethyl)-1-piperidinyl]-; 2-(4-(Trifluoromethyl)piperidin-1-yl)thiazole-5-carbaldehyde
EINECS	Contact for details

Quality Control

Our 2-[4-(Trifluoromethyl)Piperidino]-1,3-Thiazole-5-Carbaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), identity confirmation, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.