Description

(1S,2S,3R,4S,5S)-2-Amino-4,6,6-Trimethylbicyclo[3.1.1]heptane-3-carboxylic Acid Hydrochloride is a high-purity, stereochemically defined bicyclic amino acid derivative, serving as a critical chiral building block for advanced organic synthesis. Its rigid, functionalized structure makes it an invaluable intermediate for constructing complex molecules with precise three-dimensional architecture. This compound is essential for research and development in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients, chiral catalysts, and peptidomimetics.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new drug candidates, especially in central nervous system (CNS) and metabolic disease therapeutics.
• Agrochemical Synthesis: Building block for creating novel, stereoselective pesticides and herbicides with enhanced efficacy and environmental profiles.
• Peptidomimetics & Bioactive Molecule Design: Used to introduce conformational constraints into peptide chains, improving metabolic stability and target selectivity.
• Chiral Catalyst & Ligand Precursor: Serves as a starting material for synthesizing sophisticated asymmetric catalysts used in enantioselective transformations.
• Academic & Industrial R&D: A valuable tool for chemists exploring new synthetic methodologies and structure-activity relationships (SAR).
• Fine Chemical Production: Intermediate in the multi-step synthesis of specialty chemicals requiring high stereochemical purity.

Basic Information

Product Name	(1S,2S,3R,4S,5S)-2-Amino-4,6,6-Trimethylbicyclo[3.1.1]heptane-3-carboxylic Acid Hydrochloride
CAS No.	1000304-41-5
Molecular Formula	C11H20ClNO2
Molecular Weight	233.73 g/mol
Synonyms	2-Amino-4,6,6-trimethylbicyclo[3.1.1]heptane-3-carboxylic acid hydrochloride (1S,2S,3R,4S,5S)-; (1S,2S,3R,4S,5S)-rel-2-Amino-4,6,6-trimethylbicyclo[3.1.1]heptane-3-carboxylic acid hydrochloride; Bicyclo[3.1.1]heptane-3-carboxylic acid, 2-amino-4,6,6-trimethyl-, hydrochloride, (1S,2S,3R,4S,5S)-; Trimethylbicycloheptane amino acid hydrochloride
EINECS	Contact for details

Quality Control

Our (1S,2S,3R,4S,5S)-2-Amino-4,6,6-Trimethylbicyclo[3.1.1]heptane-3-carboxylic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.