Description

2-tert-Butyl-7-Chloro-4-Nitroindole is a specialized indole derivative, a key heterocyclic building block in advanced organic synthesis. This compound matters for its role as a crucial intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is needed by R&D chemists and process development scientists working on novel active ingredients, including potential pharmaceuticals and crop protection agents.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing specific receptor activity.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging the bioactivity of the indole and nitro-substituted core structure.
• Material Science: Potential building block for creating advanced organic electronic materials or specialty dyes and pigments due to its conjugated system.
• Academic & Contract Research: Essential for methodological studies in organic chemistry, including novel cross-coupling reactions and heterocyclic compound library generation.
• Chemical Biology Probes: Can be utilized to develop molecular probes for studying biological pathways and enzyme functions.

Basic Information

Product Name	2-tert-Butyl-7-Chloro-4-Nitroindole
CAS No.	1000018-53-0
Molecular Formula	C₁₂H₁₃ClN₂O₂
Molecular Weight	252.70 g/mol
Synonyms	7-Chloro-2-tert-butyl-4-nitro-1H-indole; 2-(tert-Butyl)-7-chloro-4-nitro-1H-indole; 1H-Indole, 7-chloro-2-(1,1-dimethylethyl)-4-nitro-; 7-Chloro-4-nitro-2-tert-butylindole; 2-tert-Butyl-7-chloro-4-nitro-1H-indole; 4-Nitro-2-tert-butyl-7-chloroindole
EINECS	Contact for details

Quality Control

Our 2-tert-Butyl-7-Chloro-4-Nitroindole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and residual solvents are provided and available upon request, supporting compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and strong bases. The compound may be light-sensitive; handle and store accordingly.

Specification

Item	Specification
Appearance	Yellow to brown powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.