Description

2-Bromo-1-(1,3-thiazol-2-yl)ethanone is a versatile and reactive brominated ketone building block featuring a thiazole heterocycle. This compound is of significant value in organic synthesis, particularly for the construction of complex molecules in pharmaceutical and agrochemical research. It serves as a key intermediate for medicinal chemists and R&D professionals developing new active ingredients. Its reactivity profile makes it essential for nucleophilic substitution and cross-coupling reactions.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly those targeting infectious diseases or central nervous system disorders.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiazole moiety.
• Chemical Research & Development: Employed in academic and industrial labs for methodological studies in heterocyclic chemistry and the development of new synthetic routes.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands or organocatalysts used in asymmetric synthesis.
• Material Science Precursor: Potential use in the synthesis of organic semiconductors or functional polymers with specific electronic properties.

Basic Information

Item	Detail
Product Name	2-Bromo-1-(1,3-thiazol-2-yl)ethanone
CAS No.	199804-81-4
Molecular Formula	C5H4BrNOS
Molecular Weight	206.06 g/mol
Synonyms	2-Bromo-1-(thiazol-2-yl)ethanone; 2-Acetylthiazole, 2-bromo-; 2-Bromo-2-thiazolylethanone; α-Bromo-2-acetylthiazole; 2-(2-Bromoacetyl)thiazole; 1-(1,3-Thiazol-2-yl)-2-bromoethanone; 2-Bromo-1-(1,3-thiazol-2-yl)ethan-1-one
EINECS	Contact for details

Quality Control

Our 2-Bromo-1-(1,3-thiazol-2-yl)ethanone is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.