Description

1,2,3,4-Tetrahydro-7-(Trifluoromethoxy)Isoquinoline is a specialized heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the unique combination of the isoquinoline scaffold and the trifluoromethoxy group, which is prized for modulating the physicochemical properties of target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Key pharmaceutical intermediate in the synthesis of potential central nervous system (CNS) and oncology drug candidates.
• Versatile building block for constructing complex nitrogen-containing heterocycles in medicinal chemistry.
• Precursor for the development of novel agrochemicals, including herbicides and fungicides, leveraging the metabolic stability imparted by the trifluoromethoxy group.
• Used in academic and industrial R&D for structure-activity relationship (SAR) studies and library synthesis.
• Intermediate in the synthesis of ligands for catalysis and materials science applications.
• Starting material for fine chemical and custom synthesis projects requiring functionalized tetrahydroisoquinolines.

Basic Information

Product Name	1,2,3,4-Tetrahydro-7-(Trifluoromethoxy)Isoquinoline
CAS No.	199678-30-3
Molecular Formula	C10H10F3NO
Molecular Weight	217.19 g/mol
Synonyms	7-(Trifluoromethoxy)-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydro-7-(trifluoromethoxy)isoquinoline; 7-Trifluoromethoxy-1,2,3,4-tetrahydroisoquinoline; 7-(Trifluoromethoxy)-3,4-dihydro-1H-isoquinoline; TFMO-THIQ; 199678-30-3; Tetrahydro-7-trifluoromethoxyisoquinoline
EINECS	Contact for details

Quality Control

Our 1,2,3,4-Tetrahydro-7-(Trifluoromethoxy)Isoquinoline is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent identity. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.