Description

tert-Butyl Indole-6-Carboxylate is a high-purity, protected indole derivative serving as a critical synthetic intermediate in advanced organic chemistry. This compound matters for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of drug candidates targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging the indole scaffold's bioactivity.
• Organic Synthesis Reagent: Serves as a protected carboxylate precursor in multi-step synthetic routes, including peptide mimetics and heterocyclic chemistry.
• Material Science Research: Intermediate for creating functional organic molecules with potential applications in organic electronics and photovoltaics.
• Academic & Contract Research: Essential reagent for methodological development and discovery chemistry in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	tert-Butyl Indole-6-Carboxylate
CAS No.	199589-62-3
Molecular Formula	C13H15NO2
Molecular Weight	217.26 g/mol
Synonyms	1H-Indole-6-carboxylic acid, 1,1-dimethylethyl ester; 6-(tert-Butoxycarbonyl)indole; tert-Butyl 1H-indole-6-carboxylate; Indole-6-carboxylic acid tert-butyl ester; 6-tert-Butoxycarbonylindole; TBIC; Boc-Indole-6-COOtBu
EINECS	Contact for details

Quality Control

Our tert-Butyl Indole-6-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.