Description

4,6-Difluoroindole is a high-purity fluorinated indole derivative, a crucial building block in advanced organic synthesis. This compound is valued for its role in modulating the electronic and steric properties of target molecules, enabling the development of novel materials and active pharmaceutical ingredients. It is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating complex heterocyclic frameworks.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Research: Used in the synthesis of advanced herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Material Science: Serves as a precursor for functionalized polymers and organic electronic materials, such as OLEDs and semiconductors.
• Chemical Biology: Employed as a probe or labeling agent in biochemical research due to its unique fluorinated indole structure.
• Academic & Contract Research: A versatile reagent for methodological development and the synthesis of complex natural product analogs in university and CRO laboratories.

Basic Information

Product Name	4,6-Difluoroindole
CAS No.	199526-97-1
Molecular Formula	C8H5F2N
Molecular Weight	153.13 g/mol
Synonyms	4,6-Difluoro-1H-indole; 1H-Indole, 4,6-difluoro-; 4,6-Difluoroindole; Difluoroindole; 4,6-F2-Indole
EINECS	Contact for details

Quality Control

Our 4,6-Difluoroindole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and internal quality standards. Custom purity grades and analytical packages are available to meet specific research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.