Description

Propionaldehyde-2,2,3,3,3-D5 is a deuterium-labeled isotopologue of propionaldehyde, where five hydrogen atoms are replaced with deuterium, a stable, non-radioactive isotope. This high isotopic purity is critical for applications requiring precise internal standards in quantitative mass spectrometry, eliminating interference from endogenous compounds. It is an essential reagent for researchers and analytical laboratories in the pharmaceutical, agrochemical, and environmental science sectors, particularly for metabolic studies, drug quantification, and trace analysis.

Application

• Internal Standard for Mass Spectrometry (MS): Serves as a crucial quantitative reference standard in GC-MS and LC-MS analyses for accurate measurement of native propionaldehyde or related metabolites.
• Pharmaceutical Research & Metabolism Studies: Used in pharmacokinetic and drug metabolism studies to track and quantify drug-derived compounds within biological systems.
• Analytical Method Development & Validation: Employed in developing and validating highly sensitive and specific analytical methods in compliance with regulatory guidelines (e.g., FDA, EMA).
• Environmental and Food Safety Testing: Facilitates the detection and accurate quantification of aldehydes and contaminants at trace levels in complex matrices like water, air, and food products.
• Chemical Synthesis & Mechanistic Studies: Acts as a labeled starting material or intermediate in synthetic chemistry for reaction pathway elucidation and the preparation of other deuterated compounds.

Basic Information

Product Name	Propionaldehyde-2,2,3,3,3-D5
CAS No.	198710-93-9
Molecular Formula	C3D5HO
Molecular Weight	63.12 g/mol
Synonyms	Deuterated Propionaldehyde; [2,2,3,3,3-2H5]Propionaldehyde; Propionaldehyde-d5; Propanal-2,2,3,3,3-d5; 1-Deuterio-2,2,3,3,3-pentadeuteriopropanal; Methyl-d3-dideuterioacetaldehyde; CD3CD2CHO
EINECS	Contact for details

Quality Control

Every batch of Propionaldehyde-2,2,3,3,3-D5 is produced and analyzed under strict quality management protocols to ensure exceptional chemical and isotopic purity. Our products undergo rigorous quality testing, including NMR and mass spectrometry, to ensure compliance with the high standards required for analytical and research applications. A comprehensive Certificate of Analysis (COA) detailing purity, isotopic enrichment, and solvent content is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place, ideally at 2-8°C. Due to its highly volatile and easily oxidized nature, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, open flames, and strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Isotopic Enrichment	≥ 98 atom % D
Chemical Purity (NMR)	Conforms
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.