Description

3-(5-Fluoro-Indol-3-Yl)-Pyrrolidine-2,5-Dione is a high-purity, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in the development of novel pharmaceuticals and bioactive compounds. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, especially for programs targeting central nervous system (CNS) disorders and oncology.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of potential drug candidates, particularly those with indole and pyrrolidine scaffolds.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel therapeutic agents.
• CNS Drug Development: Serves as a precursor for compounds being investigated for neurological and psychiatric applications.
• Oncology Research: Employed in the synthesis of molecules designed to modulate specific biological targets in cancer pathways.
• Chemical Biology: Utilized as a probe or tool compound in biochemical assays to study enzyme function or protein interactions.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.

Basic Information

Product Name	3-(5-Fluoro-Indol-3-Yl)-Pyrrolidine-2,5-Dione
CAS No.	198474-05-4
Molecular Formula	C12H9FN2O2
Molecular Weight	232.21 g/mol
Synonyms	5-Fluoro-3-(2,5-dioxopyrrolidin-3-yl)-1H-indole; 3-(5-Fluoro-1H-indol-3-yl)pyrrolidine-2,5-dione; 1H-Indole-3-propanoic acid, 5-fluoro-α,γ-dioxo-, (αS,γS)-rel-; 198474-05-4; 5-Fluoro-3-(2,5-dioxo-3-pyrrolidinyl)indole; 3-(5-Fluoroindol-3-yl)-2,5-pyrrolidinedione
EINECS	Contact for details

Quality Control

Our 3-(5-Fluoro-Indol-3-Yl)-Pyrrolidine-2,5-Dione is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.