Description

Bicyclo[2.2.1]Hept-2-En-7-Ol, 7-Ethynyl-, Syn- (9Ci) is a specialized bicyclic organic compound featuring both an alkene and a terminal alkyne functional group on a norbornene-like framework, making it a valuable and versatile chiral building block. This unique structure is critical for synthesizing complex molecules with precise stereochemistry, enabling the development of advanced materials and pharmaceuticals. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for applications in asymmetric synthesis, polymer modification, and ligand development.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for creating novel drug candidates with complex, three-dimensional architectures.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where its rigid bicyclic structure can impart unique biological activity and stability.
• Advanced Material Precursor: Acts as a monomer or cross-linking agent in the development of specialty polymers, resins, and functional materials with tailored thermal or mechanical properties.
• Asymmetric Catalysis Ligand Synthesis: Employed as a core structure for constructing novel chiral ligands and organocatalysts used in enantioselective transformations.
• Academic & Industrial Research: A valuable tool for methodological development in organic synthesis, including cycloaddition reactions and click chemistry applications due to its strained alkene and alkyne moieties.
• Fine Chemical Production: Utilized in the multi-step synthesis of complex fragrances, flavors, and other high-value specialty chemicals.

Basic Information

Product Name	Bicyclo[2.2.1]Hept-2-En-7-Ol, 7-Ethynyl-, Syn- (9Ci)
CAS No.	198417-99-1
Molecular Formula	C9H10O
Molecular Weight	134.18 g/mol
Synonyms	syn-7-Ethynylbicyclo[2.2.1]hept-2-en-7-ol; 7-Ethynyl-7-hydroxybicyclo[2.2.1]hept-2-ene; 7-Ethynyl-7-norbornenol; 7-Hydroxy-7-ethynylnorbornene; 2-Norbornene-7-ethynyl-7-ol; Bicyclo[2.2.1]hept-2-ene-7-ethynyl-7-ol; (1S,2R,4S)-7-Ethynyl-7-hydroxybicyclo[2.2.1]hept-2-ene (for the specific syn isomer)
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.1]Hept-2-En-7-Ol, 7-Ethynyl-, Syn- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral assay, GC for residual solvents, and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound may be sensitive to prolonged exposure to air and moisture; for long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (syn isomer)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.