Description

Morphinan-3,6-Diol, 7,8-Didehydro-4,5-Epoxy-2-(Hydroxymethyl)-17-Methy L-, (5Alpha,6Alpha)- is a high-purity pharmaceutical intermediate of significant importance in modern medicinal chemistry. This compound serves as a critical building block for the synthesis and research of advanced opioid analgesics and related therapeutic agents. It is essential for pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions focused on neuropharmacology and pain management research.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potent opioid analgesic APIs and their derivatives.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new compounds with targeted receptor activity.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Research: Employed in studies investigating opioid receptor binding, signaling pathways, and neuropharmacology.
• Process Development: Utilized in scaling up and optimizing synthetic routes for complex morphinan-based pharmaceuticals.

Basic Information

Product Name	Morphinan-3,6-Diol, 7,8-Didehydro-4,5-Epoxy-2-(Hydroxymethyl)-17-Methy L-, (5Alpha,6Alpha)-
CAS No.	198273-90-4
Molecular Formula	C₁₈H₂₁NO₄
Molecular Weight	315.36 g/mol
Synonyms	2-(Hydroxymethyl)-17-methyl-4,5α-epoxy-7,8-didehydromorphinan-3,6α-diol; 17-Methylmorphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-2-(hydroxymethyl)-, (5α,6α)-; Morphinan derivative intermediate; Opioid synthetic intermediate
EINECS	Contact for details

Quality Control

Our Morphinan-3,6-Diol, 7,8-Didehydro-4,5-Epoxy-2-(Hydroxymethyl)-17-Methy L-, (5Alpha,6Alpha)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by spectroscopic methods (IR, NMR), and residual solvent analysis to ensure it meets exacting standards for pharmaceutical research. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.