Description

5,8-Dimethoxy-1,2,3,4-Tetrahydroisoquinoline-3-Carboxylic Acid Ethyl Ester is a high-purity, synthetically valuable tetrahydroisoquinoline derivative. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in organic synthesis, enabling the construction of complex molecular architectures. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting neurological or cardiovascular systems.
• Organic Synthesis Building Block: Used in the construction of complex heterocyclic compounds and natural product analogs due to its functionalized tetrahydroisoquinoline core.
• Agrochemical Research: Employed in the development of novel pesticides and herbicides, leveraging its unique chemical scaffold.
• Chemical Reference Standard: Serves as a high-purity standard for analytical method development and quality control in R&D laboratories.
• Academic & Industrial R&D: Utilized in medicinal chemistry programs for structure-activity relationship (SAR) studies and lead optimization.

Basic Information

Product Name	5,8-Dimethoxy-1,2,3,4-Tetrahydroisoquinoline-3-Carboxylic Acid Ethyl Ester
CAS No.	198021-01-1
Molecular Formula	C₁₄H₁₉NO₄
Molecular Weight	265.31 g/mol
Synonyms	Ethyl 5,8-Dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylate; 5,8-Dimethoxy-3-ethoxycarbonyl-1,2,3,4-tetrahydroisoquinoline; 3-Carbethoxy-5,8-dimethoxy-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydro-5,8-dimethoxyisoquinoline-3-carboxylic acid ethyl ester; 5,8-Dimethoxy-3-ethoxycarbonyl-1,2,3,4-tetrahydroisoquinoline; Ethyl 5,8-dimethoxy-3,4-dihydro-1H-isoquinoline-3-carboxylate
EINECS	Contact for details

Quality Control

Our production of 5,8-Dimethoxy-1,2,3,4-Tetrahydroisoquinoline-3-Carboxylic Acid Ethyl Ester adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS). We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring full traceability and compliance with your research or manufacturing specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.