Description

Chloro-1H-Indole-1-Carboxylate CAS NO 197775-88-5 is a high-purity, versatile indole derivative used as a critical synthetic intermediate in advanced organic chemistry. This compound is essential for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for lead optimization and scale-up synthesis.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the synthesis of specialized polymers and organic electronic materials.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in heterocyclic and medicinal chemistry.
• Custom Synthesis: A starting material for the contract manufacturing of proprietary compounds and bespoke chemical entities for clients.

Basic Information

Product Name	Chloro-1H-Indole-1-Carboxylate
CAS No.	197775-88-5
Molecular Formula	C9H6ClNO2
Molecular Weight	195.60 g/mol
Synonyms	1-Chloroindole-1-carboxylate; 1H-Indole-1-carboxylic acid, 1-chloro-; Methyl 1-chloro-1H-indole-1-carboxylate (common salt form); 1-Chloroindole-1-carboxylic acid ester; Chloroindole carboxylate; 197775-88-5; 1-Carbomethoxy-1-chloroindole
EINECS	Contact for details

Quality Control

Our Chloro-1H-Indole-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.