Description

8-Azabicyclo[3.2.1]Octan-2-One,8-Methyl-6-Propyl-,(1R,5R,6R)-Rel-(9Ci) is a high-purity, stereochemically defined bicyclic lactam building block of significant interest in advanced organic synthesis. Its rigid, three-dimensional scaffold makes it a critical intermediate for constructing complex molecular architectures with precise spatial orientation. This compound is primarily needed by pharmaceutical R&D and fine chemical organizations focused on developing novel active ingredients and chiral catalysts.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and antiviral therapies.
• Asymmetric Catalyst Ligand Precursor: Used to develop novel ligands for transition metal catalysis, enabling stereoselective synthesis.
• Advanced Material Research: Serves as a building block for specialty polymers and functional materials with unique structural properties.
• Agrochemical Synthesis: Employed in the creation of novel, biologically active compounds with specific stereochemical requirements.
• Academic & Institutional Research: Utilized in synthetic methodology development and the study of structure-activity relationships (SAR).
• Custom Synthesis & Contract Manufacturing: A valuable starting material for bespoke chemical manufacturing services (CMS) producing high-value target molecules.

Basic Information

Product Name	8-Azabicyclo[3.2.1]Octan-2-One,8-Methyl-6-Propyl-,(1R,5R,6R)-Rel-(9Ci)
CAS No.	197588-52-6
Molecular Formula	C11H19NO
Molecular Weight	181.27 g/mol
Synonyms	(1R,5R,6R)-8-Methyl-6-propyl-8-azabicyclo[3.2.1]octan-2-one; rel-(1R,5R,6R)-8-Methyl-6-propyl-8-azabicyclo[3.2.1]octan-2-one; 8-Methyl-6-propyl-8-azabicyclo[3.2.1]octan-2-one, (1R,5R,6R)-rel-; Bicyclic Lactam Derivative; 8-Azabicyclo[3.2.1]octan-2-one, 8-methyl-6-propyl-, (1R,5R,6R)-rel-; (1R,5R,6R)-rel-8-Methyl-6-propyl-8-azabicyclo[3.2.1]octan-2-one
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch undergoes comprehensive analytical characterization, including chiral purity verification, to ensure reproducible stereochemical integrity and chemical purity. Certificates of Analysis (COA) detailing identity, assay, and impurity profiles are provided with each shipment. We support development and commercial projects requiring material produced under GMP-like controls upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.