Description

(1E)-2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-N'-hydroxyethanimidamide is a high-purity chemical building block of significant interest in advanced organic synthesis. This compound matters as a versatile intermediate, particularly valued for its role in constructing complex heterocyclic scaffolds and functionalized molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially those containing isoindole or hydroxamic acid-related pharmacophores.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators requiring specific heterocyclic structures.
• Chemical Biology Probe Synthesis: Serves as a precursor for creating molecular probes targeting enzymes like histone deacetylases (HDACs) due to its hydroxamic acid derivative potential.
• Material Science Precursor: Can be utilized in the synthesis of specialty polymers and functional organic materials with tailored properties.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the exploration of new synthetic pathways.

Basic Information

Product Name	(1E)-2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-N'-hydroxyethanimidamide
CAS No.	197083-26-4
Molecular Formula	C10H9N3O3
Molecular Weight	219.20 g/mol
Synonyms	N-Hydroxy-2-(1,3-dioxoisoindolin-2-yl)acetimidamide; (E)-N'-Hydroxy-2-(1,3-dioxoisoindolin-2-yl)ethanimidamide; 2-(1,3-Dioxoisoindolin-2-yl)-N-hydroxyacetimidamide; 2-(1,3-Dioxo-2,3-dihydro-1H-isoindol-2-yl)-N'-hydroxyethanimidamide; CAS 197083-26-4; Isoindole-1,3-dione derivative; Phthalimide acetimidamide oxime derivative
EINECS	Contact for details

Quality Control

Our (1E)-2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-N'-hydroxyethanimidamide is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.