Description

Bicyclo[3.1.0]Hexan-2-One, (1S,5R)- is a high-purity, chiral bicyclic ketone of significant interest in advanced organic synthesis. This compound serves as a critical, stereochemically defined building block for the development of novel pharmaceuticals and complex natural products. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and fine chemical industries for constructing intricate molecular architectures with precise three-dimensional control.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) and antiviral drugs.
• Agrochemical Research: Used in the creation of novel, stereoselective pesticides and herbicides where the specific spatial orientation of the molecule is crucial for biological activity.
• Fine Chemical Synthesis: Employed as a versatile precursor for complex natural product synthesis and the preparation of specialty chemicals requiring the bicyclo[3.1.0]hexane scaffold.
• Asymmetric Catalysis Ligand Precursor: Can be utilized in the development of novel chiral ligands and organocatalysts for enantioselective transformations.
• Material Science Research: Investigated as a monomer or building block for creating polymers with unique structural and physical properties derived from its strained ring system.

Basic Information

Product Name	Bicyclo[3.1.0]Hexan-2-One, (1S,5R)-
CAS No.	196488-92-3
Molecular Formula	C6H8O
Molecular Weight	96.13 g/mol
Synonyms	(1S,5R)-Bicyclo[3.1.0]hexan-2-one; (1S,5R)-Bicyclo[3.1.0]hexan-2-one; (1S,5R)-2-Bicyclo[3.1.0]hexanone; (-)-(1S,5R)-Bicyclo[3.1.0]hexan-2-one; (1S,5R)-(-)-Bicyclo[3.1.0]hexan-2-one; endo-Bicyclo[3.1.0]hexan-2-one (specific enantiomer); Bicyclo[3.1.0]hexan-2-one, (1S-cis)-
EINECS	Contact for details

Quality Control

Our Bicyclo[3.1.0]Hexan-2-One, (1S,5R)- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing specifications such as chiral purity, chemical purity (by GC/HPLC), and identity confirmation. We adhere to cGMP standards where applicable to meet the stringent requirements of our pharmaceutical and research partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place at controlled room temperature (15-25°C). Due to its highly volatile nature, ensure containers are properly sealed and stored upright. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Chiral Purity (Chiral GC/HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.