Description

2H-Isoxazolo[3,2-A]Isoquinoline,2-Ethoxy-1,5,6,10B-Tetrahydro-,(2R,10Br)-Rel-(9Ci) CAS NO 196393-34-7 is a high-purity, stereochemically defined heterocyclic compound belonging to the fused isoxazolo-isoquinoline class. This compound serves as a critical chiral building block or advanced pharmaceutical intermediate in the synthesis of complex bioactive molecules. It is primarily required by research institutions and pharmaceutical development companies engaged in medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new therapeutic agents, particularly in central nervous system (CNS) or oncology targets.
• Medicinal Chemistry Research: Used as a scaffold or precursor in structure-activity relationship (SAR) studies and lead optimization programs.
• Process Chemistry Development: Serves as a standard or starting material for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Asymmetric Synthesis: Utilized in catalytic or stoichiometric reactions to introduce complex stereochemistry into target molecules.
• Chemical Reference Standard: Acts as a high-purity analytical standard for method development and quality control in API manufacturing.
• Academic Research: Employed in universities and institutes for studying novel heterocyclic reactions and synthetic methodologies.

Basic Information

Product Name	2H-Isoxazolo[3,2-A]Isoquinoline,2-Ethoxy-1,5,6,10B-Tetrahydro-,(2R,10Br)-Rel-(9Ci)
CAS No.	196393-34-7
Molecular Formula	C₁₅H₁₇NO₂
Molecular Weight	243.30 g/mol
Synonyms	(2R,10bR)-2-Ethoxy-1,5,6,10b-tetrahydro-2H-isoxazolo[3,2-a]isoquinoline; rel-(2R,10bR)-2-Ethoxy-1,5,6,10b-tetrahydro-2H-isoxazolo[3,2-a]isoquinoline; 2H-Isoxazolo[3,2-a]isoquinoline, 2-ethoxy-1,5,6,10b-tetrahydro-, (2R,10bR)-rel-; 196393-34-7; (rel)-(2R,10bR)-2-Ethoxy-1,5,6,10b-tetrahydro-2H-isoxazolo[3,2-a]isoquinoline.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for advanced pharmaceutical intermediates. Every batch is characterized using advanced analytical techniques including HPLC, GC, NMR, and MS to confirm identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing all relevant specifications are available upon request. We support development under quality systems suitable for cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.