Description

tert-Butyl 7-Bromo-3,4-Dihydro-1H-Pyrido[3,4-B]Indole-2(9H)-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of complex bioactive molecules, particularly in medicinal chemistry. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, where precise chemical architecture is critical for biological activity.

Application

This specialized intermediate serves as a crucial component in several high-value synthetic pathways within the pharmaceutical and research sectors.

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore and optimize the biological profile of new chemical entities.
• API Development: Serves as a building block in the research and development stages of new Active Pharmaceutical Ingredients (APIs).
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client projects.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	tert-Butyl 7-Bromo-3,4-Dihydro-1H-Pyrido[3,4-B]Indole-2(9H)-Carboxylate
CAS No.	196203-96-0
Molecular Formula	C16H19BrN2O2
Molecular Weight	351.24 g/mol
Synonyms	7-Bromo-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole-2-carboxylic acid tert-butyl ester; tert-Butyl 7-bromo-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-2-carboxylate; 7-Bromo-2,3,4,9-tetrahydro-1H-β-carboline-2-carboxylic acid tert-butyl ester; 7-Bromo-THBC-OtBu; Boc-7-Bromo-tetrahydro-β-carboline
EINECS	Contact for details

Quality Control

Our production of tert-Butyl 7-Bromo-3,4-Dihydro-1H-Pyrido[3,4-B]Indole-2(9H)-Carboxylate adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.