Description

3,4-Dihydroisoquinoline-2(1H)-Sulfonyl Chloride(Saltdata: Free) is a specialized sulfonyl chloride derivative, a key building block in organic synthesis. This compound is valued for its high reactivity, enabling the efficient introduction of the sulfonamide moiety into target molecules. It is primarily required by pharmaceutical and agrochemical research & development teams for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, where the sulfonamide group can enhance biological activity.
• Chemical Biology & Proteomics: Serves as a reactive handle for labeling proteins or modifying biomolecules in research applications.
• Material Science Research: Employed in the creation of novel polymers or functional materials with specific sulfonated properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects.

Basic Information

Product Name	3,4-Dihydroisoquinoline-2(1H)-Sulfonyl Chloride(Saltdata: Free)
CAS No.	195987-27-0
Molecular Formula	C9H8ClNO2S
Molecular Weight	229.68 g/mol
Synonyms	1,2,3,4-Tetrahydroisoquinoline-2-sulfonyl chloride; 2,3,4-Tetrahydro-1H-isoquinoline-2-sulfonyl chloride; 2-Sulfonylchloride-1,2,3,4-tetrahydroisoquinoline; 3,4-Dihydro-1H-isoquinoline-2-sulfonyl chloride; 3,4-Dihydroisoquinoline-2-sulfonyl chloride; Tetrahydroisoquinoline-2-sulfonyl chloride
EINECS	Contact for details

Quality Control

Our 3,4-Dihydroisoquinoline-2(1H)-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.