Description

Dimethyl 2-(1,2-Dithiolan-3-Yl)Malonate is a specialized organic compound featuring a 1,2-dithiolane (lipoyl) moiety esterified with a malonate group. This unique structure makes it a valuable key intermediate and building block in advanced organic synthesis, particularly for the development of novel pharmaceuticals and bioactive molecules. It is primarily sought after by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in creating complex sulfur-containing compounds and exploring new therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially those targeting metabolic pathways or requiring lipoic acid analogs.
• Biochemical Research: Used as a building block for synthesizing probes, inhibitors, or labeled compounds to study enzyme mechanisms and cellular processes involving thiol-disulfide exchange.
• Agrochemical Development: Serves as an intermediate in the research and production of new generation pesticides or herbicides with specific modes of action.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value specialty chemicals for various industrial applications.
• Material Science Research: Potential monomer or modifier in the development of polymers with unique redox-responsive or adhesive properties.

Basic Information

Item	Details
Product Name	Dimethyl 2-(1,2-Dithiolan-3-Yl)Malonate
CAS No.	195724-22-2
Molecular Formula	C9H12O4S2
Molecular Weight	248.32 g/mol
Synonyms	Dimethyl (R/S)-2-(1,2-Dithiolan-3-yl)malonate; 2-(1,2-Dithiolan-3-yl)propanedioic acid dimethyl ester; DL-2-(1,2-Dithiolan-3-yl)malonic acid dimethyl ester; Malonic acid, 2-(1,2-dithiolan-3-yl)-, dimethyl ester; (±)-Dimethyl 2-(1,2-dithiolan-3-yl)malonate; Lipoylmalonate dimethyl ester
EINECS	Contact for details

Quality Control

Our Dimethyl 2-(1,2-Dithiolan-3-Yl)Malonate is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC for purity and spectroscopic identification (IR, NMR), to ensure it meets exacting standards for research and development use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). The compound may be sensitive to moisture and oxidation over prolonged periods; consider storage under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.