Description

Pradofloxacin Hydrochloride is a synthetic, broad-spectrum fluoroquinolone antibiotic specifically developed for veterinary use. Its primary value lies in its enhanced activity against both Gram-positive and Gram-negative bacteria, including strains resistant to earlier-generation quinolones. This compound is essential for manufacturers in the veterinary pharmaceutical industry developing treatments for skin, soft tissue, and urinary tract infections in companion animals, particularly dogs and cats.

Application

• Veterinary Pharmaceutical Formulations: As the active pharmaceutical ingredient (API) in oral tablets, topical solutions, and injectables for companion animals.
• Treatment of Bacterial Infections: Specifically for canine and feline pyoderma, wound infections, and urinary tract infections (UTIs) caused by susceptible organisms.
• Research & Development: Used as a reference standard in analytical laboratories for method development and quality control testing of veterinary products.
• Antimicrobial Susceptibility Testing: Serves as a critical component in microbiological studies to determine bacterial resistance profiles.
• Veterinary Generic Drug Manufacturing: Sourced by generic drug manufacturers for producing cost-effective therapeutic alternatives.

Basic Information

Product Name	Pradofloxacin Hydrochloride
CAS No.	195532-14-0
Molecular Formula	C21H25F3N4O4 • HCl
Molecular Weight	502.91 g/mol
Synonyms	Pradofloxacin HCl; Veraflox (Veterinary Trade Name); 8-Cyano-1-cyclopropyl-7-[(1S,6S)-2,8-diazabicyclo[4.3.0]non-8-yl]-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid hydrochloride; BAY 35-3376; (1S,6S)-8-Cyano-1-cyclopropyl-6-fluoro-1,4-dihydro-7-(2,8-diazabicyclo[4.3.0]non-8-yl)-4-oxo-3-quinolinecarboxylic acid hydrochloride
EINECS	Contact for details

Quality Control

Our Pradofloxacin Hydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, to ensure it meets high-purity standards suitable for pharmaceutical use. A Certificate of Analysis (COA) detailing identity, purity, residual solvents, and related substances is provided with each shipment, supporting compliance with veterinary GMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. The original container should be kept sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.