Description

4-[(4-Bromothien-2-Yl)Methyl]Morpholine is a high-value brominated heterocyclic building block that combines a morpholine moiety with a substituted thiophene ring. This compound is critical for medicinal chemistry and pharmaceutical research, serving as a versatile intermediate in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and antiviral therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its unique bromine handle for further functionalization.
• Agrochemical Synthesis: Serves as a building block for developing novel pesticides and herbicides with specific biological activity.
• Ligand and Catalyst Development: The morpholine and thiophene groups make it a candidate for designing novel ligands in catalytic systems.
• Material Science Precursor: Potential use in the synthesis of organic semiconductors and conductive polymers due to the thiophene backbone.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for use in multi-step custom synthesis projects for clients.

Basic Information

Product Name	4-[(4-Bromothien-2-Yl)Methyl]Morpholine
CAS No.	194851-19-9
Molecular Formula	C9H12BrNOS
Molecular Weight	262.17 g/mol
Synonyms	4-[(4-Bromothiophen-2-yl)methyl]morpholine; 2-[(Morpholin-4-yl)methyl]-4-bromothiophene; 4-Bromo-2-morpholinomethylthiophene; 4-(4-Bromo-2-thienylmethyl)morpholine; 4-(4-Bromothien-2-ylmethyl)morpholine; Morpholine, 4-[(4-bromo-2-thienyl)methyl]-
EINECS	Contact for details

Quality Control

Our 4-[(4-Bromothien-2-Yl)Methyl]Morpholine is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and development. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.