Description

Bicyclo[3.1.0]Hexane-6-Carboxylic Acid, 2-(Carboxyamino)-, (1R,5S,6R)-Rel-[Partial]- (9Ci) is a high-purity, stereochemically defined bicyclic amino acid derivative, serving as a critical chiral building block in advanced organic synthesis. Its unique constrained structure and functional groups make it invaluable for constructing complex molecular architectures with precise three-dimensional control. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, process development, and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in areas requiring rigid, bicyclic scaffolds.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and the synthesis of compound libraries for drug discovery programs targeting CNS disorders, infectious diseases, and metabolic conditions.
• Peptidomimetics: Incorporation into peptide analogs to enhance metabolic stability, bioavailability, and receptor selectivity by introducing conformational constraints.
• Agrochemical Research: Serves as a building block for developing novel herbicides, fungicides, or insecticides with improved efficacy and environmental profiles.
• Asymmetric Synthesis Catalyst Ligand: Potential use in the development of chiral ligands or organocatalysts for enantioselective transformations.
• Chemical Biology Probes: Useful for creating molecular probes to study enzyme mechanisms or protein-protein interactions in biological systems.

Basic Information

Product Name	Bicyclo[3.1.0]Hexane-6-Carboxylic Acid, 2-(Carboxyamino)-, (1R,5S,6R)-Rel-[Partial]- (9Ci)
CAS No.	194735-94-9
Molecular Formula	C8H11NO4
Molecular Weight	185.18 g/mol
Synonyms	(1R,5S,6R)-2-(Carboxyamino)bicyclo[3.1.0]hexane-6-carboxylic Acid; 2-Aminocarbonylbicyclo[3.1.0]hexane-6-carboxylic Acid (relative stereochemistry); Bicyclo[3.1.0]hexane-6-carboxylic acid, 2-(aminocarbonyl)-, (1R,5S,6R)-rel-; 194735-94-9; (1R,5S,6R)-rel-2-Carbamoylbicyclo[3.1.0]hexane-6-carboxylic Acid
EINECS	Contact for details

Quality Control

Our Bicyclo[3.1.0]Hexane-6-Carboxylic Acid, 2-(Carboxyamino)-, (1R,5S,6R)-Rel-[Partial]- (9Ci) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC for stereochemical purity and NMR for structural confirmation. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere or with desiccant for long-term preservation to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.