Description

o-Toluidine-D9 is a deuterated isotopologue of o-toluidine, where nine hydrogen atoms are replaced by deuterium, a stable hydrogen isotope. This high isotopic purity is critical for applications requiring non-radioactive isotopic labeling, such as internal standards in mass spectrometry to ensure precise and accurate quantitative analysis. It is an essential material for researchers and quality control laboratories in the pharmaceutical, agrochemical, and environmental testing sectors, where tracking molecular pathways and achieving definitive identification are paramount.

Application

• Internal Standard for Mass Spectrometry (MS): Serves as a critical quantitative reference standard in LC-MS and GC-MS analysis for the quantification of o-toluidine and related compounds in complex matrices.
• Metabolic Pathway Tracing: Used in pharmaceutical and biochemical research to study the metabolism, distribution, and excretion of toluidine-based compounds using deuterium as a stable isotopic tracer.
• Environmental Analysis: Employed in the detection and accurate quantification of trace levels of toluidine isomers in environmental samples (water, soil) for regulatory compliance and safety monitoring.
• Pharmaceutical Impurity Profiling: Aids in the identification and measurement of process-related impurities and degradation products in active pharmaceutical ingredients (APIs) and finished drug products.
• Dye and Pigment Intermediate Research: Acts as a labeled precursor in the development and analysis of azo dyes and pigments, helping to understand reaction mechanisms and purity.
• Forensic and Toxicological Analysis: Provides a definitive standard for the confirmatory testing of toluidine exposure or contamination in forensic and clinical toxicology laboratories.

Basic Information

Product Name	o-Toluidine-D9
CAS No.	194423-47-7
Molecular Formula	C7D9N
Molecular Weight	111.20 g/mol
Synonyms	2-Methylaniline-D9; 2-Aminotoluene-D9; 2-Methylbenzenamine-D9; o-Methylaniline-D9; Deuterated o-Toluidine; 1-Amino-2-methylbenzene-D9; (2-Methylphenyl)amine-D9; o-Tolylamine-D9
EINECS	Contact for details

Quality Control

Every batch of o-Toluidine-D9 is manufactured and analyzed under strict quality systems to ensure the highest isotopic and chemical purity for demanding analytical applications. Our products undergo rigorous quality testing, including NMR and mass spectrometry, to confirm deuterium incorporation and chemical identity. Certificates of Analysis (COA) detailing isotopic purity (atom % D), chemical purity (by HPLC/GC), and specific analytical data are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR / NMR)	Conforms to structure
Purity (HPLC / GC)	≥ 98.0%
Isotopic Purity (Atom % D)	≥ 98.0% (by MS)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.