Description

(5α)-8,9-Didehydro-6,8-Dimethylergoline CAS NO 194346-16-2 is a high-purity ergoline alkaloid derivative, a key intermediate in advanced pharmaceutical synthesis. This compound matters for its critical role in the research and development of novel therapeutic agents targeting neurological and cardiovascular systems. It is primarily needed by pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and academic research institutions focused on medicinal chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of complex ergot alkaloid-based active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in the discovery and development of new drug candidates targeting serotonin and dopamine receptors.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Research: Employed in studies investigating the biological activity and mechanism of action of ergoline derivatives.
• Process Development: Utilized in scaling up and optimizing synthetic routes for the production of related pharmaceutical compounds.

Basic Information

Product Name	(5α)-8,9-Didehydro-6,8-Dimethylergoline
CAS No.	194346-16-2
Molecular Formula	C16H18N2
Molecular Weight	238.33 g/mol
Synonyms	8,9-Didehydro-6,8-dimethylergoline; 5α-Ergoline-8,9-didehydro-6,8-dimethyl; 6,8-Dimethyl-8,9-didehydroergoline; (5α)-6,8-Dimethyl-8,9-didehydroergoline; 8,9-Didehydro-6,8-dimethylergoline (5α-isomer); 6,8-Dimethyl-δ8,9-ergoline
EINECS	Contact for details

Quality Control

Our (5α)-8,9-Didehydro-6,8-Dimethylergoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and should be handled under an inert atmosphere when appropriate to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.