Description

8-Indolizinecarboxylicacid,7-Aminooctahydro-,Methylester,(8R,8As)-Rel- CAS NO 193341-62-7 is a high-purity, stereochemically defined indolizine derivative, a crucial advanced intermediate in modern synthetic organic chemistry. Its value lies in its complex, multifunctional structure, which serves as a versatile scaffold for constructing more complex molecules, particularly in pharmaceutical research and development. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients and complex natural product analogs.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting neurological or metabolic disorders.
• Agrochemical Research: Used as a precursor in the development of new pesticides or herbicides with complex heterocyclic structures.
• Fine Chemical Synthesis: Serves as a chiral template or advanced intermediate for the production of specialty chemicals, flavors, and fragrances.
• Academic & Institutional Research: Employed in university and institutional labs for methodological development in organic synthesis and catalysis studies.
• Process Chemistry Development: Utilized for scaling up synthetic routes and optimizing manufacturing processes for complex molecules in pilot plants.
• Bioconjugation & Probe Development: Potential use in creating chemical probes or bioconjugates for biochemical and diagnostic applications due to its reactive amine and ester functional groups.

Basic Information

Item	Details
Product Name	8-Indolizinecarboxylicacid,7-Aminooctahydro-,Methylester,(8R,8As)-Rel-
CAS No.	193341-62-7
Molecular Formula	C11H18N2O2
Molecular Weight	210.27 g/mol
Synonyms	rel-(8R,8aS)-7-Aminooctahydroindolizine-8-carboxylic acid methyl ester; Methyl (8R,8aS)-7-aminooctahydroindolizine-8-carboxylate; 7-Aminooctahydroindolizine-8-carboxylic acid methyl ester, (8R,8aS)-rel-; (rel-8R,8aS)-Methyl 7-amino-1,2,3,5,6,7,8,8a-octahydroindolizine-8-carboxylate; Octahydroindolizine derivative CAS 193341-62-7; Indolizine-8-carboxylic acid, 7-aminooctahydro-, methyl ester, (8R,8aS)-rel-
EINECS	Contact for details

Quality Control

Our 8-Indolizinecarboxylicacid,7-Aminooctahydro-,Methylester,(8R,8As)-Rel- is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and chiral purity analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.