Description

1H-Indole-1-Carboxylic Acid, 5-Fluoro-3-Iodo-, 1,1-Dimethylethyl Ester is a high-purity, multi-functionalized indole derivative serving as a critical building block in advanced organic synthesis. This compound is engineered to provide a versatile and reactive scaffold for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that leverage the indole core structure.
• Material Science: Serves as a monomer or functional additive in the creation of specialty polymers and advanced organic electronic materials.
• Chemical Biology & Proteomics: Employed as a molecular probe or a tag in activity-based protein profiling (ABPP) and bioconjugation strategies.
• Academic & Contract Research: Essential reagent for methodological development in organic chemistry and for exploring new reaction pathways involving halogenated indoles.

Basic Information

Product Name	1H-Indole-1-Carboxylic Acid, 5-Fluoro-3-Iodo-, 1,1-Dimethylethyl Ester
CAS No.	192189-13-2
Molecular Formula	C13H13FINO2
Molecular Weight	361.15 g/mol
Synonyms	tert-Butyl 5-Fluoro-3-iodo-1H-indole-1-carboxylate; 5-Fluoro-3-iodo-1H-indole-1-carboxylic acid 1,1-dimethylethyl ester; 1-(tert-Butoxycarbonyl)-5-fluoro-3-iodoindole; Boc-5-Fluoro-3-iodoindole; 5-Fluoro-3-iodoindole-1-carboxylic acid tert-butyl ester; 3-Iodo-5-fluoro-1H-indole-1-carboxylic acid tert-butyl ester; N-Boc-5-fluoro-3-iodoindole
EINECS	Contact for details

Quality Control

Our 1H-Indole-1-Carboxylic Acid, 5-Fluoro-3-Iodo-, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.