Description

3-Iodo-5-Methoxyindole-1-Carboxylic Acid tert-Butyl Ester is a high-value, protected indole derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in providing a versatile, functionalized scaffold for constructing complex heterocyclic molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process R&D teams in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-purity building blocks for drug discovery and process optimization.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel indole-based active pharmaceutical ingredients (APIs) and drug candidates targeting various therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and combinatorial chemistry libraries to explore new chemical entities.
• Agrochemical Synthesis: Intermediate in the development of advanced crop protection agents and plant growth regulators.
• Fine Chemical Production: Serves as a precursor for specialized dyes, pigments, and advanced materials requiring functionalized indole cores.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and complex molecule synthesis.

Basic Information

Product Name	3-Iodo-5-Methoxyindole-1-Carboxylic Acid tert-Butyl Ester
CAS No.	192189-10-9
Molecular Formula	C14H16INO3
Molecular Weight	373.19 g/mol
Synonyms	1-*tert*-Butoxycarbonyl-3-iodo-5-methoxyindole; 3-Iodo-5-methoxy-1H-indole-1-carboxylic acid 1,1-dimethylethyl ester; *tert*-Butyl 3-iodo-5-methoxy-1H-indole-1-carboxylate; 3-Iodo-5-methoxyindole-1-carboxylic acid 1,1-dimethylethyl ester; Boc-3-Iodo-5-methoxyindole; 1-Boc-3-Iodo-5-methoxyindole; 192189-10-9; 3-Iodo-5-methoxy-1-indolecarboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 3-Iodo-5-Methoxyindole-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.