Description

1-(tert-Butoxycarbonyl)-3-Iodo-1H-Indole is a protected indole derivative, a crucial synthetic intermediate in modern organic chemistry. Its core value lies in enabling the controlled functionalization of the indole scaffold, a privileged structure in medicinal chemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the synthesis of complex bioactive molecules and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of drug candidates targeting neurological disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a precursor for functional organic materials, including organic light-emitting diodes (OLEDs) and conductive polymers.
• Academic & R&D: A versatile reagent for methodological development in cross-coupling reactions (e.g., Suzuki, Sonogashira) and indole chemistry studies.
• Peptidomimetics: Employed in the construction of indole-containing peptide analogs and protease inhibitors.
• Chemical Library Synthesis: A valuable scaffold for generating diverse compound libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	1-(tert-Butoxycarbonyl)-3-Iodo-1H-Indole
CAS No.	192189-07-4
Molecular Formula	C13H14INO2
Molecular Weight	343.16 g/mol
Synonyms	3-Iodo-1H-indole-1-carboxylic acid 1,1-dimethylethyl ester; 1-Boc-3-iodoindole; tert-Butyl 3-iodo-1H-indole-1-carboxylate; 3-Iodo-1-Boc-indole; N-Boc-3-iodoindole; 1-(tert-Butoxycarbonyl)-3-iodoindole; 3-Iodo-N-Boc-indole; Boc-3-I-indole
EINECS	Contact for details

Quality Control

Our 1-(tert-Butoxycarbonyl)-3-Iodo-1H-Indole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.