Description

Bicyclo[3.1.0]Hexane-6-Carboxylic Acid, 2-Amino-2-Cyano-4-Methyl-, Ethyl Ester is a high-value, multifunctional bicyclic building block in advanced organic synthesis. This compound matters for its unique constrained geometry and the presence of three distinct reactive handles—an amino group, a cyano group, and an ester—enabling the construction of complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, catalyst design, and the synthesis of novel heterocycles.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of new pesticides and herbicides, leveraging its bicyclic scaffold for enhanced biological activity and stability.
• Ligand and Catalyst Development: The amino and ester functionalities make it a valuable starting material for creating novel chiral ligands and organocatalysts.
• Advanced Material Chemistry: Employed in the research and development of specialty polymers and functional materials with tailored properties.
• Academic and R&D Laboratories: A versatile tool for methodological studies in organic synthesis, including cycloaddition reactions and ring-expansion chemistry.
• Peptidomimetics and Bioisosteres: Its rigid, three-dimensional structure is ideal for designing conformationally restricted peptide analogs and bioisosteric replacements in medicinal chemistry.

Basic Information

Product Name	Bicyclo[3.1.0]Hexane-6-Carboxylic Acid, 2-Amino-2-Cyano-4-Methyl-, Ethyl Ester
CAS No.	191399-79-8
Molecular Formula	C11H14N2O2
Molecular Weight	206.24 g/mol
Synonyms	Ethyl 2-Amino-2-cyano-4-methylbicyclo[3.1.0]hexane-6-carboxylate; 2-Amino-2-cyano-4-methylbicyclo[3.1.0]hexane-6-carboxylic Acid Ethyl Ester; 6-Carbethoxy-2-amino-2-cyano-4-methylbicyclo[3.1.0]hexane; Bicyclo[3.1.0]hexane-6-carboxylic acid, 2-amino-2-cyano-4-methyl-, ethyl ester; 191399-79-8; Amino-cyano-methyl bicyclohexane ethyl ester
EINECS	Contact for details

Quality Control

Our Bicyclo[3.1.0]Hexane-6-Carboxylic Acid, 2-Amino-2-Cyano-4-Methyl-, Ethyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and scale-up. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to verify identity and purity. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.