Description

Bicyclo[3.1.0]Hexane-1-Carboxylic Acid, 2-Oxo-, Methyl Ester, (1S)- (9Ci) is a high-value, chiral bicyclic lactone derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique strained ring structure and defined stereochemistry make it indispensable for constructing complex molecular architectures with high precision. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of complex drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where its bicyclic framework contributes to unique biological activity.
• Asymmetric Catalysis Research: Serves as a valuable substrate or ligand precursor in the development and study of new asymmetric catalytic reactions.
• Material Science Precursor: Employed in the synthesis of specialized polymers and organic electronic materials that require rigid, stereodefined monomers.
• Academic & Process Chemistry: Utilized in university and industrial R&D for methodological studies, total synthesis projects, and scale-up process optimization.
• Flavor & Fragrance Intermediate: Acts as a starting material for the synthesis of high-value odorants and flavor compounds with complex olfactory profiles.

Basic Information

Product Name	Bicyclo[3.1.0]Hexane-1-Carboxylic Acid, 2-Oxo-, Methyl Ester, (1S)- (9Ci)
CAS No.	191281-14-8
Molecular Formula	C8H10O3
Molecular Weight	154.16 g/mol
Synonyms	(1S)-2-Oxobicyclo[3.1.0]hexane-1-carboxylic acid methyl ester; Methyl (1S)-2-oxobicyclo[3.1.0]hexane-1-carboxylate; (1S)-Methyl 2-oxobicyclo[3.1.0]hexane-1-carboxylate; (-)-Methyl 2-oxobicyclo[3.1.0]hexane-1-carboxylate; (1S,5R)-Methyl 2-oxobicyclo[3.1.0]hexane-1-carboxylate; Bicyclo[3.1.0]hexane-1-carboxylic acid, 2-oxo-, methyl ester, (1S)-; Chiral bicyclic lactone ester
EINECS	Contact for details

Quality Control

Every batch of our Bicyclo[3.1.0]Hexane-1-Carboxylic Acid, 2-Oxo-, Methyl Ester, (1S)- (9Ci) is manufactured under strict quality management systems. We employ advanced analytical techniques, including chiral HPLC, GC, and NMR, to ensure exceptional chemical and enantiomeric purity for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.