Description

(S)-4-Isopropyl-5,5-Diphenyloxazolidine-2-Thione is a high-purity chiral oxazolidinethione derivative, serving as a critical building block and chiral auxiliary in advanced organic synthesis. Its value lies in enabling the stereoselective construction of complex molecules, ensuring high enantiomeric purity in final products. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require precise chirality control for developing active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of enantiomerically pure active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Acts as a chiral auxiliary or ligand in metal-catalyzed reactions to induce stereoselectivity.
• Agrochemical Research: Used in the synthesis of chiral pesticides and herbicides where specific stereochemistry impacts biological activity.
• Catalyst Development: Component in the design of novel organocatalysts for green chemistry applications.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry and new reaction development.
• Fine Chemical Production: Building block for specialty chemicals requiring defined stereochemistry, such as flavors, fragrances, and advanced materials.

Basic Information

Product Name	(S)-4-Isopropyl-5,5-Diphenyloxazolidine-2-Thione
CAS No.	191274-53-0
Molecular Formula	C18H19NOS
Molecular Weight	297.41 g/mol
Synonyms	(4S)-4-(1-Methylethyl)-5,5-diphenyl-2-thioxo-1,3-oxazolidine; (S)-4-Isopropyl-5,5-diphenyl-2-thioxooxazolidine; (S)-5,5-Diphenyl-4-isopropyloxazolidine-2-thione; (S)-4-Isopropyl-5,5-diphenyl-2-oxazolidinethione; Chiral Evans Auxiliary Derivative; (S)-Diphenylisopropyloxazolidinethione
EINECS	Contact for details

Quality Control

Our (S)-4-Isopropyl-5,5-Diphenyloxazolidine-2-Thione is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for synthetic applications. A Certificate of Analysis (COA) detailing identity, purity (typically ≥98%), and enantiomeric excess is provided with every shipment to guarantee batch-to-batch consistency and reliable performance in your processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.