Description

3-(2-Trifluoromethyl-Phenyl)-Propan-1-Ol is a versatile fluorinated aromatic alcohol intermediate of significant importance in advanced organic synthesis. Its value lies in the unique reactivity and stability imparted by the trifluoromethyl group, making it a critical building block for high-performance materials and active pharmaceutical ingredients. This compound is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce fluorine motifs into complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in CNS and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Building block for advanced herbicides, fungicides, and pesticides where the CF3 group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Used in the synthesis of fluorinated components for electronic display and lighting technologies.
• Polymer & Resin Modifier: Imparts specific hydrophobic and chemical resistance properties to specialty polymers and coatings.
• Organic Synthesis Reagent: Serves as a versatile precursor for further functionalization via the hydroxyl group in custom synthesis and contract manufacturing.
• Fluorine Chemistry Research: Essential compound for academic and industrial research exploring new fluorination methodologies and structure-activity relationships.

Basic Information

Product Name	3-(2-Trifluoromethyl-Phenyl)-Propan-1-Ol
CAS No.	191155-81-4
Molecular Formula	C10H11F3O
Molecular Weight	204.19 g/mol
Synonyms	3-[2-(Trifluoromethyl)phenyl]propan-1-ol; 2-(Trifluoromethyl)benzenepropanol; 1-Propanol, 3-[2-(trifluoromethyl)phenyl]-; 3-(2-Trifluoromethylphenyl)-1-propanol; α,α,α-Trifluoro-o-toluylpropanol; 2-Trifluoromethylphenylpropanol; (2-Trifluoromethylphenyl)propyl alcohol; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 3-(2-Trifluoromethyl-Phenyl)-Propan-1-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container must be kept tightly closed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.