Description

(S)-(+)-2-Amino-2-(4-tert-Butylphenyl)Ethanol is a high-value chiral amino alcohol building block, essential for the synthesis of enantiomerically pure pharmaceuticals and fine chemicals. Its defined stereochemistry provides a critical advantage in creating active pharmaceutical ingredients (APIs) with high specificity and reduced side effects. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors for developing new chiral catalysts and therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure drugs, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Chiral Ligand & Catalyst Precursor: Used in asymmetric synthesis to create ligands for metal-catalyzed reactions, enabling high enantioselectivity in C-C bond formation.
• Agrochemical Synthesis: Employed in the development of chiral pesticides and herbicides where specific stereochemistry is required for biological activity and environmental safety.
• Resolution Agent: Utilized as a resolving agent for the separation of racemic mixtures of carboxylic acids or other chiral compounds.
• Material Science Research: Serves as a building block for chiral polymers, liquid crystals, and other functional materials with optical properties.
• Academic & Process R&D: A valuable compound for methodological development in organic chemistry and scale-up process optimization in pilot plants.

Basic Information

Product Name	(S)-(+)-2-Amino-2-(4-tert-Butylphenyl)Ethanol
CAS No.	191109-50-9
Molecular Formula	C12H19NO
Molecular Weight	193.29 g/mol
Synonyms	(S)-(+)-2-Amino-2-(4-tert-butylphenyl)ethanol; (S)-2-Amino-1-(4-tert-butylphenyl)ethanol; (S)-2-Amino-2-(4-(1,1-dimethylethyl)phenyl)ethanol; (S)-1-(4-tert-Butylphenyl)-2-aminoethanol; (S)-α-(Aminomethyl)-4-tert-butylbenzenemethanol; (S)-2-Amino-2-(p-tert-butylphenyl)ethanol; (S)-4-tert-Butylphenylglycinol; (S)-2-Amino-1-(4-tert-butylphenyl)ethan-1-ol
EINECS	Contact for details

Quality Control

Our production of (S)-(+)-2-Amino-2-(4-tert-Butylphenyl)Ethanol adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized by advanced analytical techniques including chiral HPLC, NMR, and optical rotation measurement. Certificates of Analysis (COA) detailing purity, enantiomeric excess (ee), and impurity profiles are provided with every shipment. Our quality system is designed to support cGMP compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Specific Rotation [α]	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.