Description

(R)-(+)-5,5-Diphenyl-4-Benzyl-2-Oxazolidinone is a high-value, enantiomerically pure chiral auxiliary and building block widely used in asymmetric synthesis. Its core value lies in enabling the stereoselective construction of complex molecules, ensuring high enantiomeric excess in final products. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise control over molecular chirality for developing active ingredients and specialty chemicals.

Application

• Asymmetric Synthesis: Serves as a versatile chiral auxiliary for the enantioselective alkylation, aldol, and Diels-Alder reactions.
• Pharmaceutical Intermediates: Critical for the research and production of enantiomerically pure active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and cardiovascular drug candidates.
• Agrochemical Development: Used in the synthesis of chiral herbicides, fungicides, and pesticides where specific stereochemistry is required for bioactivity.
• Catalyst and Ligand Preparation: Acts as a precursor for novel chiral catalysts and ligands used in homogeneous catalysis.
• Academic & Industrial R&D: A key reagent in methodological development for organic and medicinal chemistry research.
• Fine Chemical Production: Employed in the custom synthesis of complex, high-value specialty chemicals and flavors/fragrances.

Basic Information

Product Name	(R)-(+)-5,5-Diphenyl-4-Benzyl-2-Oxazolidinone
CAS No.	191090-40-1
Molecular Formula	C22H19NO2
Molecular Weight	329.40 g/mol
Synonyms	(R)-4-Benzyl-5,5-diphenyl-2-oxazolidinone; (R)-(+)-4-Benzyl-5,5-diphenyloxazolidin-2-one; (R)-5,5-Diphenyl-4-benzyl-2-oxazolidinone; (R)-N-Benzyl-α,α-diphenylprolinol Oxazolidinone; Evans Auxiliary (R)-type derivative; (R)-4-Benzyl-3,3-diphenyloxazolidin-2-one; (R)-α,α-Diphenylprolinol Benzyl Ether Cyclic Carbamate
EINECS	Contact for details

Quality Control

Our (R)-(+)-5,5-Diphenyl-4-Benzyl-2-Oxazolidinone is manufactured under strict quality systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized by advanced analytical techniques including HPLC, chiral chromatography, and NMR to confirm identity, chemical purity, and enantiomeric excess (ee). Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.