Description

(R)-(+)-4-Isopropyl-5,5-Diphenyl-2-Oxazolidinone is a high-purity, chiral oxazolidinone derivative widely used as a versatile chiral auxiliary and building block in asymmetric synthesis. Its value lies in enabling the stereoselective construction of complex molecules, which is critical for developing pharmaceuticals and advanced materials. This product is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality chiral reagents.

Application

• As a chiral auxiliary in the enantioselective alkylation, aldol, and Diels-Alder reactions.
• Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates.
• Intermediate in the research and development of agrochemicals and specialty fine chemicals.
• Used in catalyst ligand preparation for asymmetric catalysis.
• Employed in academic and industrial R&D for methodological studies in organic synthesis.
• Precursor for the synthesis of other chiral oxazolidinone derivatives with tailored properties.

Basic Information

Product Name	(R)-(+)-4-Isopropyl-5,5-Diphenyl-2-Oxazolidinone
CAS No.	191090-32-1
Molecular Formula	C18H19NO2
Molecular Weight	281.35 g/mol
Synonyms	(4R)-4-(1-Methylethyl)-5,5-diphenyl-2-oxazolidinone; (R)-4-Isopropyl-5,5-diphenyloxazolidin-2-one; (R)-(+)-4-Isopropyl-5,5-diphenyl-2-oxazolidinone; Evans Chiral Auxiliary Derivative; (R)-4-iPr-5,5-Ph2-oxazolidinone
EINECS	Contact for details

Quality Control

Our (R)-(+)-4-Isopropyl-5,5-Diphenyl-2-Oxazolidinone is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including chiral purity and chemical identity verification, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.