Description

Geranylgeranyl Thiol is a specialized organosulfur compound featuring a long-chain terpenoid structure. This molecule is of significant interest in biochemical research and synthesis due to its role as a key intermediate in the biosynthesis of various natural products and as a potential building block for lipidated peptides and proteins. It is primarily utilized by research institutions and pharmaceutical development companies engaged in the study of protein prenylation, enzyme mechanisms, and the synthesis of bioactive compounds. Its unique structure makes it a valuable tool for probing biological pathways and developing novel therapeutic agents.

Application

• Biochemical Research: Critical intermediate in the study of protein prenylation, a key post-translational modification for membrane association and function of proteins like Ras and Rab GTPases.
• Pharmaceutical Development: Serves as a building block for synthesizing lipidated peptides, enzyme inhibitors, and other bioactive molecules targeting prenylation-related diseases.
• Enzyme Mechanism Studies: Used as a substrate or inhibitor to investigate the activity and specificity of prenyltransferases and other sulfur-processing enzymes.
• Synthesis of Natural Products: Key precursor in the chemical synthesis of complex terpenoids and sulfur-containing natural products with potential biological activity.
• Chemical Biology Probes: Utilized to create labeled or tagged analogs for visualizing and tracking protein prenylation in cellular systems.
• Material Science Research: Potential monomer or modifier for creating novel polymers with specific hydrophobic or self-assembly properties derived from its terpenoid chain.

Basic Information

Product Name	Geranylgeranyl Thiol
CAS No.	191022-18-1
Molecular Formula	C₂₀H₃₄S
Molecular Weight	306.55 g/mol
Synonyms	(all-E)-Geranylgeranethiol; (all-E)-3,7,11,15-Tetramethyl-2,6,10,14-hexadecatetraene-1-thiol; Farnesylgeraniol Thiol; GGThiol; GG-SH; Prenyl Thiol C20; 2,6,10,14-Hexadecatetraene-1-thiol, 3,7,11,15-tetramethyl-, (all-E)-
EINECS	Contact for details

Quality Control

Our Geranylgeranyl Thiol is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency suitable for research applications. Each lot is characterized using advanced analytical techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your critical research and development work.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to maximize stability. This compound is sensitive to oxidation and moisture; ensure containers are sealed tightly after each use to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Isomeric Purity (GC/HPLC)	≥ 90% (all-E isomer)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.