Description

1,2,3,4-Tetrahydro-3-Isoquinoline Carboxylic Acid Hydrobromide is a high-purity organic salt derivative of the tetrahydroisoquinoline scaffold, valued for its role as a critical building block in advanced pharmaceutical synthesis. This compound is essential for research and development in medicinal chemistry, particularly for creating novel drug candidates targeting the central nervous system. It is primarily sought by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in organic synthesis and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of potent bioactive molecules and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a core scaffold for developing novel compounds with potential therapeutic applications in neurology and psychiatry.
• Process Chemistry Development: Serves as a starting material or intermediate in optimizing scalable synthetic routes for drug candidates.
• Biochemical Research: Employed in studies investigating enzyme inhibition or receptor-ligand interactions due to its specific structural features.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	1,2,3,4-Tetrahydro-3-Isoquinoline Carboxylic Acid Hydrobromide
CAS No.	190961-50-3
Molecular Formula	C₁₀H₁₁NO₂·HBr
Molecular Weight	258.11 g/mol
Synonyms	3-Carboxy-1,2,3,4-tetrahydroisoquinoline Hydrobromide; 1,2,3,4-Tetrahydroisoquinoline-3-carboxylic Acid HBr; THIQ-3-COOH HBr; 3-(Carboxymethyl)-3,4-dihydro-1H-isoquinoline Hydrobromide; (1,2,3,4-Tetrahydro-3-isoquinolinyl)carboxylic Acid Hydrobromide; 190961-50-3; Tetrahydroisoquinoline-3-carboxylic Acid Hydrobromide Salt
EINECS	Contact for details

Quality Control

Our 1,2,3,4-Tetrahydro-3-Isoquinoline Carboxylic Acid Hydrobromide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards for research and pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.