Description

(S)-1,2,3,4-Tetrahydro-3-Isoquinolinecarboxylic Acid Hydrobromide is a high-purity chiral building block and salt form of a key isoquinoline derivative. This compound is of significant value in pharmaceutical research and development, particularly for its role as a precursor in the synthesis of active pharmaceutical ingredients (APIs) and complex organic molecules. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for creating novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the asymmetric synthesis of drug candidates targeting neurological and cardiovascular disorders.
• API Synthesis: Used as a building block in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs).
• Peptidomimetics Research: Serves as a constrained amino acid analog in the design and development of novel peptidomimetic compounds.
• Asymmetric Catalysis: Employed as a chiral ligand precursor or auxiliary in stereoselective catalytic reactions.
• Medicinal Chemistry: Utilized in structure-activity relationship (SAR) studies and lead optimization programs.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	(S)-1,2,3,4-Tetrahydro-3-Isoquinolinecarboxylic Acid Hydrobromide
CAS No.	190961-15-0
Molecular Formula	C10H12BrNO2
Molecular Weight	258.11 g/mol
Synonyms	(S)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid hydrobromide; (3S)-1,2,3,4-Tetrahydro-3-isoquinolinecarboxylic Acid Hydrobromide; (S)-Tic-OH·HBr; (S)-1,2,3,4-Tetrahydro-3-isoquinolinecarboxylic Acid HBr; H-Tic-OH·HBr; (S)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic Acid HBr Salt; (S)-3-Carboxy-1,2,3,4-tetrahydroisoquinoline Hydrobromide
EINECS	Contact for details

Quality Control

Our (S)-1,2,3,4-Tetrahydro-3-Isoquinolinecarboxylic Acid Hydrobromide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.