Description

6-Oxabicyclo[3.1.0]Hexan-2-Ol, 1-Methyl- is a high-purity, specialized bicyclic ether-alcohol compound that serves as a critical chiral building block and intermediate in advanced organic synthesis. Its unique oxabicyclo[3.1.0]hexane scaffold provides a rigid, three-dimensional structure valuable for constructing complex molecular architectures with precise stereochemistry. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to synthesize novel active ingredients and fine chemicals.

Application

The unique structural features of 1-Methyl-6-oxabicyclo[3.1.0]hexan-2-ol make it a versatile intermediate for demanding synthetic applications.

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its bicyclic structure can contribute to biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to control stereoselectivity.
• Fine Chemical Production: Employed in the multistep synthesis of complex fragrance molecules, flavors, and other high-value specialty chemicals.
• Material Science Research: Investigated as a monomer or cross-linking agent for creating novel polymers with specific thermal or mechanical properties.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic chemistry, including ring-opening reactions and stereochemical investigations.

Basic Information

Product Name	6-Oxabicyclo[3.1.0]Hexan-2-Ol, 1-Methyl-
CAS No.	190895-93-3
Molecular Formula	C6H10O2
Molecular Weight	114.14 g/mol
Synonyms	1-Methyl-6-oxabicyclo[3.1.0]hexan-2-ol; 1-Methyl-6-oxabicyclo[3.1.0]hexane-2-ol; (1R,2S,5S)-rel-1-Methyl-6-oxabicyclo[3.1.0]hexan-2-ol; 6-Oxabicyclo[3.1.0]hexan-2-ol, 1-methyl-; Bicyclic ether-alcohol intermediate; Oxabicyclohexanol derivative
EINECS	Contact for details

Quality Control

Our 6-Oxabicyclo[3.1.0]Hexan-2-Ol, 1-Methyl- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. All products undergo rigorous analytical testing, including HPLC, GC, and NMR, to confirm identity, purity, and chiral integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support cGMP compliance for pharmaceutical applications and can tailor quality protocols to meet specific customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere to maintain stability and prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0% (Standard Grade)
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (Enantiomerically Enriched Grade)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.