Description

p-Cresol-D8 is a deuterated isotopologue of p-cresol, where eight hydrogen atoms are replaced by deuterium, offering exceptional isotopic purity for advanced analytical and research applications. This compound is critical for use as an internal standard in mass spectrometry and NMR spectroscopy, enabling precise quantification and metabolic pathway tracing in complex biological and chemical matrices. It is essential for researchers and quality control laboratories in the pharmaceutical, agrochemical, and environmental analysis sectors who require high-fidelity isotopic labels to ensure data accuracy and regulatory compliance.

Application

• Internal Standard for Quantitative GC-MS or LC-MS Analysis of cresols and related phenolic compounds in biological fluids and environmental samples.
• Deuterated Tracer in Metabolic Studies and pharmacokinetic research within pharmaceutical development.
• NMR Spectroscopy Solvent and Shift Reference for structural elucidation and reaction monitoring in organic chemistry.
• Isotope Dilution Mass Spectrometry (IDMS) for achieving high-accuracy measurements in certified reference material production.
• Research and Development of deuterated pharmaceuticals, agrochemicals, and specialty materials.
• Use in Stable Isotope Labeling experiments to study reaction mechanisms and degradation pathways.

Basic Information

Product Name	p-Cresol-D8
CAS No.	190780-66-6
Molecular Formula	C7D8O
Molecular Weight	116.21 g/mol
Synonyms	4-Methylphenol-d8; 4-Cresol-d8; p-Methylphenol-d8; [2H8]-4-Cresol; 4-Hydroxytoluene-d8; Perdeuterated p-cresol; 1-Hydroxy-4-(trideuteriomethyl)benzene-2,3,5,6-tetradeuterio; Deuterated p-Cresol (D8)
EINECS	Contact for details

Quality Control

Every batch of our p-Cresol-D8 is manufactured and analyzed under strict quality management protocols to ensure exceptional isotopic and chemical purity. We provide comprehensive Certificates of Analysis (COA) detailing key parameters such as isotopic enrichment (Atom % D), chemical purity by HPLC, and identity confirmation. Our quality system is designed to meet the rigorous demands of analytical reference standard applications, supporting compliance with GLP and ISO 17025 principles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR / NMR)	Conforms to structure
Isotopic Purity (Atom % D)	≥ 98% (D8)
Chemical Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.