Description

5-Bromoisoquinolin-1(2H)-One is a high-purity brominated isoquinoline derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a reactive halogen handle and a fused heterocyclic scaffold, enabling the construction of complex molecules for pharmaceutical and materials research. This compound is essential for medicinal chemists and R&D professionals in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting neurological disorders and oncology.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides by providing a versatile heterocyclic core.
• Ligand Synthesis: Serves as a starting material for creating complex ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the research and development of organic electronic materials, such as OLEDs and semiconductors.
• Chemical Biology Probes: Utilized to create tool compounds and probes for studying biological pathways and enzyme functions.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting exploratory synthetic chemistry.

Basic Information

Product Name	5-Bromoisoquinolin-1(2H)-One
CAS No.	190777-77-6
Molecular Formula	C9H6BrNO
Molecular Weight	224.06 g/mol
Synonyms	5-Bromoisoquinolin-1(2H)-one; 5-Bromo-1,2-dihydroisoquinolin-1-one; 5-Bromo-1H-isoquinolin-1-one; 5-Bromo-2H-isoquinolin-1-one; 5-Bromoisoquinolinone; 1(2H)-Isoquinolinone, 5-bromo-; 5-Bromo-1-isoquinolinol; 190777-77-6
EINECS	Contact for details

Quality Control

Our 5-Bromoisoquinolin-1(2H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for use in regulated research environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.