Description

Firocoxib is a highly selective non-steroidal anti-inflammatory drug (NSAID) belonging to the coxib class, specifically targeting the COX-2 enzyme. This targeted action makes it a valuable active pharmaceutical ingredient (API) for managing pain and inflammation with a potentially improved safety profile regarding gastrointestinal effects compared to non-selective NSAIDs. It is primarily utilized in the veterinary pharmaceutical industry for the development of analgesic and anti-inflammatory treatments for companion animals and livestock. Firocoxib CAS NO 189954-96-9 is a critical component for formulators seeking to create effective veterinary therapeutics.

Application

• Veterinary Pharmaceutical API: Primary use as the active ingredient in oral pastes, tablets, and injectables for dogs and horses.
• Canine Osteoarthritis Management: Formulated for long-term pain relief and improved mobility in dogs suffering from degenerative joint disease.
• Equine Musculoskeletal Disorders: Used in treatments for inflammation and pain associated with lameness and other conditions in horses.
• Post-Operative Analgesia: Incorporated into therapeutic regimens for managing pain following surgical procedures in animals.
• Research & Development: Serves as a reference standard and key intermediate in pharmaceutical R&D for novel anti-inflammatory agents.
• Generic Veterinary Drug Manufacturing: Essential for producers of generic veterinary medicines requiring a reliable, high-quality COX-2 inhibitor.

Basic Information

Product Name	Firocoxib
CAS No.	189954-96-9
Molecular Formula	C17H20O5S
Molecular Weight	336.41 g/mol
Synonyms	3-(Cyclopropylmethoxy)-5,5-dimethyl-4-[4-(methylsulfonyl)phenyl]furan-2(5H)-one; Previcox (Veterinary Trade Name); Firocoxibum; COX-2 Inhibitor V; UNII-8U6EA6W5TK; 4-[4-(Methylsulfonyl)phenyl]-3-(cyclopropylmethoxy)-5,5-dimethyl-2(5H)-furanone
EINECS	Contact for details

Quality Control

Our Firocoxib is manufactured under strict quality management systems to ensure it meets the high standards required for pharmaceutical use. Every batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via advanced techniques like HPLC. A Certificate of Analysis (COA) is provided with each shipment, detailing compliance with established specifications. We support compliance with cGMP (current Good Manufacturing Practice) guidelines for active pharmaceutical ingredients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.