Description

Ethyl 5-Chlorothiophene-3-Carboxylate is a high-purity organic building block and heterocyclic intermediate of significant commercial importance. This compound is valued for its role as a versatile synthon in the development of advanced pharmaceutical actives and specialty agrochemicals. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex thiophene-containing molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the chlorothiophene moiety.
• Material Science Research: Serves as a monomer or building block for developing conjugated polymers and organic electronic materials for applications like organic photovoltaics (OPVs) and field-effect transistors (OFETs).
• Chemical Research & Development: Employed in academic and industrial labs for method development, catalysis studies, and the creation of novel chemical libraries for high-throughput screening.
• Ligand and Catalyst Preparation: Useful for synthesizing specialized ligands and organocatalysts used in asymmetric synthesis and transition metal catalysis.

Basic Information

Product Name	Ethyl 5-Chlorothiophene-3-Carboxylate
CAS No.	189331-32-6
Molecular Formula	C7H7ClO2S
Molecular Weight	190.65 g/mol
Synonyms	5-Chlorothiophene-3-carboxylic acid ethyl ester; Ethyl 5-chloro-3-thiophenecarboxylate; 3-Thiophenecarboxylic acid, 5-chloro-, ethyl ester; 5-Chloro-3-thiophenecarboxylic acid ethyl ester; 5-Chloro-thiophene-3-carboxylic acid ethyl ester; Ethyl 5-chlorothiophene-3-carboxylate; 189331-32-6
EINECS	Contact for details

Quality Control

Our Ethyl 5-Chlorothiophene-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.