Description

5-Bromo-2-Chlorothiophene-3-Carboxylic Acid is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound is valued for its unique thiophene core, which serves as a versatile scaffold for constructing complex molecules with tailored electronic and biological properties. It is primarily sought after by research chemists and process development teams in the pharmaceutical, agrochemical, and materials science industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, leveraging the bioactivity of the thiophene moiety.
• Material Science Precursor: Serves as a building block for conjugated polymers, organic semiconductors, and non-linear optical (NLO) materials due to its electron-rich heterocyclic structure.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical manufacturing.
• Academic & Industrial R&D: Utilized in research laboratories for method development, exploring new chemical reactions, and creating compound libraries for screening.

Basic Information

Product Name	5-Bromo-2-Chlorothiophene-3-Carboxylic Acid
CAS No.	189330-38-9
Molecular Formula	C5H2BrClO2S
Molecular Weight	241.49 g/mol
Synonyms	5-Bromo-2-chloro-3-thiophenecarboxylic acid; 2-Chloro-5-bromothiophene-3-carboxylic acid; 3-Thiophenecarboxylic acid, 5-bromo-2-chloro-; 189330-38-9; 5-Bromo-2-chlorothiophene-3-carboxylic acid; 2-Chloro-5-bromo-3-thiophenecarboxylic acid; 5-Br-2-Cl-thiophene-3-COOH
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-2-Chlorothiophene-3-Carboxylic Acid is manufactured and tested under strict quality management protocols to ensure consistency and reliability for your critical applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles as confirmed by advanced analytical techniques (HPLC, GC, NMR).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and sources of ignition. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.