Description

5-Bromo-4-Methylthiophene-2-Carboxamide is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for lead optimization and scale-up activities.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the thiophene scaffold's bioactivity.
• Material Science: Serves as a monomer or functional unit in the creation of conductive polymers, organic semiconductors, and advanced organic frameworks.
• Chemical Synthesis: Acts as a versatile building block for further functionalization via cross-coupling reactions, amide bond transformations, and halogen-metal exchange.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the discovery of new chemical entities.

Basic Information

Product Name	5-Bromo-4-Methylthiophene-2-Carboxamide
CAS No.	189330-08-3
Molecular Formula	C7H8BrNOS
Molecular Weight	234.11 g/mol
Synonyms	5-Bromo-4-methyl-2-thiophenecarboxamide; 2-Thiophenecarboxamide, 5-bromo-4-methyl-; 4-Methyl-5-bromothiophene-2-carboxamide; 5-Bromo-4-methylthiophene-2-carboxylic acid amide; 189330-08-3; 5-Br-4-Me-thiophene-2-CONH2
EINECS	Contact for details

Quality Control

Our 5-Bromo-4-Methylthiophene-2-Carboxamide is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our quality commitment ensures the material meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.