Description

Ethyl 3-(3-(tert-Butylthio)-1-(4-Chlorobenzyl)-5-(Quinolin-2-Ylmethoxy)-1H-Indol-2-Yl)-2,2-Dimethylpropanoate is a high-purity, complex organic intermediate of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block for the synthesis of novel therapeutic agents, particularly in the fields of oncology and immunology. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries.

Application

• Pharmaceutical Intermediate: Key synthetic precursor for the development of new chemical entities (NCEs) and active pharmaceutical ingredients (APIs).
• Oncology Research: Used in the synthesis of potential small-molecule inhibitors targeting specific cellular pathways.
• Immunomodulator Development: Serves as a core structure for creating compounds that modulate immune system responses.
• Process Chemistry: Employed in route scouting, optimization, and scale-up activities for new drug candidates.
• Academic & Contract Research: Utilized in university and CRO (Contract Research Organization) settings for exploratory medicinal chemistry programs.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and validation.

Basic Information

Product Name	Ethyl 3-(3-(tert-Butylthio)-1-(4-Chlorobenzyl)-5-(Quinolin-2-Ylmethoxy)-1H-Indol-2-Yl)-2,2-Dimethylpropanoate
CAS No.	189239-02-9
Molecular Formula	C36H39ClN2O3S
Molecular Weight	615.22 g/mol
Synonyms	Ethyl 3-[3-(tert-Butylthio)-1-[(4-chlorophenyl)methyl]-5-[(quinolin-2-yl)methoxy]-1H-indol-2-yl]-2,2-dimethylpropanoate; 1-(4-Chlorobenzyl)-3-(tert-butylthio)-5-(quinolin-2-ylmethoxy)-1H-indole-2-propanoic acid, 2,2-dimethyl-, ethyl ester; CAS 189239-02-9; 189239-02-9; 2,2-Dimethyl-3-[1-[(4-chlorophenyl)methyl]-3-[(1,1-dimethylethyl)thio]-5-[(2-quinolinyl)methoxy]-1H-indol-2-yl]propanoic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 3-(3-(tert-Butylthio)-1-(4-Chlorobenzyl)-5-(Quinolin-2-Ylmethoxy)-1H-Indol-2-Yl)-2,2-Dimethylpropanoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and current industry best practices for research-grade intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric oxygen.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.