Description

1H-Thieno[3,4-D]Imidazole-4-Pentanamide, n-[2-(Ethylamino)Ethyl]Hexahydro-2-Oxo-, (3As,4S,6Ar)- is a sophisticated heterocyclic organic compound with a complex fused-ring structure, serving as a critical advanced intermediate in modern pharmaceutical synthesis. Its precise stereochemistry and functional groups make it an invaluable building block for developing novel active pharmaceutical ingredients (APIs) with targeted therapeutic effects. This high-purity intermediate is essential for research institutions and pharmaceutical manufacturers engaged in the development of innovative small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel, complex drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• API Development: Used in the research and process development stages for creating new Active Pharmaceutical Ingredients (APIs) requiring a specific thienoimidazole scaffold.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore new chemical entities and optimize drug-like properties.
• Process Chemistry: Serves as a defined intermediate in scale-up and optimization of synthetic routes for more efficient and cost-effective API production.
• Contract Manufacturing (CMO): Supplied to contract development and manufacturing organizations (CDMOs) for cGMP production of clinical trial materials and commercial drug substances.
• Bioconjugation & Prodrug Synthesis: Its functional groups allow for its use in creating targeted drug delivery systems or prodrug formulations.

Basic Information

Product Name	1H-Thieno[3,4-D]Imidazole-4-Pentanamide, n-[2-(Ethylamino)Ethyl]Hexahydro-2-Oxo-, (3As,4S,6Ar)-
CAS No.	189209-29-8
Molecular Formula	C15H24N4O2S
Molecular Weight	324.44 g/mol
Synonyms	(3aS,4S,6aR)-Hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanamide, N-[2-(ethylamino)ethyl]-; (3aS,4S,6aR)-N-[2-(Ethylamino)ethyl]hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanamide; 1H-Thieno[3,4-d]imidazole-4-pentanamide, N-[2-(ethylamino)ethyl]hexahydro-2-oxo-, (3aS,4S,6aR)-; Stereoisomer of Biotin derivative; Advanced Biotin analog intermediate; Thienoimidazole pentanamide derivative
EINECS	Contact for details

Quality Control

Our production of this advanced pharmaceutical intermediate adheres to stringent quality systems. Every batch is manufactured under controlled conditions and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided, detailing specifications for chiral purity, chemical purity (typically ≥97% by HPLC), and relevant impurities. We support development from research to commercial scale with quality standards appropriate for each phase.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Related Substances (HPLC)	Individual unknown impurity ≤ 0.5% Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.