Description

3-Aminomethyl-Indole-1-Carboxylic Acid tert-Butyl Ester is a versatile and high-value protected indole derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in providing a reactive aminomethyl handle while protecting the indole nitrogen and carboxylic acid functionalities, enabling precise and selective chemical transformations. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and complex heterocyclic molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of drug candidates targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Peptidomimetic Chemistry: Used to incorporate indole-based scaffolds into peptide analogs to enhance stability and biological activity.
• Agrochemical Synthesis: Building block for creating novel fungicides, herbicides, and plant growth regulators with indole core structures.
• Material Science Research: Monomer or precursor for synthesizing specialized polymers and organic electronic materials.
• Chemical Biology Probes: Utilized in the development of fluorescent tags and molecular probes for studying biological processes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and libraries for high-throughput screening.

Basic Information

Product Name	3-Aminomethyl-Indole-1-Carboxylic Acid tert-Butyl Ester
CAS No.	188988-46-7
Molecular Formula	C15H20N2O2
Molecular Weight	260.33 g/mol
Synonyms	1H-Indole-1-carboxylic acid, 3-(aminomethyl)-, 1,1-dimethylethyl ester; tert-Butyl 3-(aminomethyl)-1H-indole-1-carboxylate; 3-(Aminomethyl)indole-1-carboxylic Acid tert-Butyl Ester; Boc-3-aminomethylindole; 1-Boc-3-aminomethylindole; 3-Aminomethyl-1H-indole-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-3-(aminomethyl)indole
EINECS	Contact for details

Quality Control

Our 3-Aminomethyl-Indole-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.